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Illustrative only

GeographyUS

Attractiveness vs probability of success

Horizontal: market attractiveness (0–5) · Vertical: probability of success · Mark area: peak sales, base case

CardiovascularRenalMetabolic

The illustrative portfolio prioritised: ATTR cardiomyopathy and Heart failure (HFrEF) combine high probability of success with near-term launches, while Type 2 diabetes sits lowest on both axes. Marks are coloured by therapy area.