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Illustrative only

GeographyUS
Addressable patients3,400,000
Probability of success, base10%
Potential launchQ4 ’33
Peak sales · Base case$350m
Risk-adjusted peak sales$35m
Development spend, next 12 months2%

Market attractiveness

  • Market size5 / 5
  • Unmet need2 / 5
  • Competitive headroom1 / 5
  • Pricing potential1.5 / 5

Why it sits where it does

The largest addressable population and the lowest risk-adjusted value: crowded, cheap and early.

0–5 = attractiveness. A crowded market or a high bar scores low.

Assessment summary

Next decision

Phase I completion 2028 – PoS 10% → 15% if positive.

The nine modules behind this summary are built out on Heart failure (HFrEF) in this preview.

Open the HFrEF workspace